✦ LIBER ✦

Pharmacokinetics of mebudipine, a new calcium antagonist, following single intravenous and oral administrations in rats

✍ Scribed by Shahab Bohlooli; Fariborz Keyhanfar; Massoud Mahmoudian

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 70 KB
Volume: 25
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bdd.400

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacokinetics of α-dihydroergocriptin

Pharmacokinetics of α-dihydroergocriptine in rats after single intravenous and single and repeated oral administrations

✍ G. Coppi; S. Silingardi 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 440 KB 👁 2 views

The pharmacokinetics of a-dihydroergocriptine methane sulphonate in rats were investigated using an HPLC method for the detection of unchanged adihydroergocriptine (DHEK) in plasma, organs (kidneys, heart, lungs, spleen, liver, and brain), and urine. The plasma profile of DHEK obtained after intrave

Comparative pharmacokinetics of single d

Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration in rats

✍ Andries Pelser; Douw G. Müller; Jeanetta du Plessis; Jan L. du Preez; Colleen Go 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 72 KB 👁 1 views

Pharmacokinetics of single oral and mult

Pharmacokinetics of single oral and multiple intravenous and oral administration of acebutolol enantiomers in a rat model

✍ S. Abolfazl Mostafavi; Robert T. Foster 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB 👁 2 views

Acebutolol (AC), is a chiral, i-adrenergic blocking agent which possesses partial agonist activity and is metabolized to an equipotent chiral metabolite, diacetolol (DC). The enantiomeric disposition of AC is reported following racemic administration as a single oral (p.o., 50 mg kg -1 ) or as a mul

Pharmacokinetics and metabolism of nefer

Pharmacokinetics and metabolism of neferine in rats after a single oral administration

✍ Ying Huang; Yun Bai; Libo Zhao; Ting Hu; Benrong Hu; Jialing Wang; Jizhou Xiang 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 211 KB 👁 2 views

Pharmacokinetics of a new reversible pro

Pharmacokinetics of a new reversible proton pump inhibitor, YH1885, after intravenous and oral administrations to rats and dogs: hepatic first-pass effect in rats

✍ Kye S. Han; Yoon G. Kim; Joong K. Yoo; Jong W. Lee; Myung G. Lee 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB 👁 1 views

The pharmacokinetics of YH1885 were evaluated after intravenous (iv) and oral administrations of the drug to rats and dogs. The reason for the low extent of bioavailability (F) of YH1885 after oral administration of the drug to rats and the absorption of the drug from various rat gastrointestinal (G

PHARMACOKINETICS OF THE ENANTIOMERS OF V

PHARMACOKINETICS OF THE ENANTIOMERS OF VERAPAMIL AFTER INTRAVENOUS AND ORAL ADMINISTRATION OF RACEMIC VERAPAMIL IN A RAT MODEL

✍ M. MASOOD BHATTI; ROBERT T. FOSTER 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB 👁 2 views

Verapamil is a chiral calcium channel blocking drug which is useful clinically as the racemate in treating hypertension and arrhythmia. The published pharmacokinetic data for verapamil enantiomers in the rat model are limited. Utilizing a stereospeci®c highperformance liquid chromatographic (HPLC) a