Pharmacokinetics of lithium in rat brain
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Subbaraya Ramaprasad; Elzbieta Ripp; Jiaxiong Pi; Melvin Lyon
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Article
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2005
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Elsevier Science
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English
β 186 KB
Lithium (Li) and its salts have been demonstrated to be the most effective drug in both acute and prophylactic treatment of bipolar disorder. The exact molecular mechanisms and particular target regions accounting for its mood-stabilizing effect remain unknown. Knowledge of Li distribution and its r