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Pharmacokinetics of liposomal aerosolized cyclosporine A for pulmonary immunosuppression

โœ Scribed by George V Letsou; Hazim J Safi; Michael J Reardon; Mehmet Ergenoglu; Zheng Li; Christos N Klonaris; John C Baldwin; Brian E Gilbert; John C Waldrep

Book ID
117041030
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
226 KB
Volume
68
Category
Article
ISSN
0003-4975

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๐Ÿ“œ SIMILAR VOLUMES

Pharmacokinetics of two alternative dosa
Pharmacokinetics of two alternative dosage forms for cyclosporine: Liposomes and intralipid
โœ S. Venkataram; W. M. Awni; K. Jordan; Y. E. Rahman ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 515 KB

Cyclosporine (CsA), commercially available as iv or oral Sandimmune, is a potent immunosuppressant which can induce dose-related nephrotoxocity. In addition, the iv product contains a solubilizing agent, Cremophore EL, which in itself is reported to be nephrotoxic and can induce, in sensitized patie