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Pharmacokinetics of lansoprazole with multiple oral and intravenous doses

✍ Scribed by James W. Freston; Mitchell A. Roseberg; Janice S. Griffin; Nancy L. Lukasik; Wei-jian Pan


Book ID
119391019
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
26 KB
Volume
96
Category
Article
ISSN
0002-9270

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The pharmacokinetics of a new serotonin 5-HT 2 antagonist, deramciclane, was studied. Single oral doses of 1, 3, 6 and 10 mg kg -1 and intravenous doses of 1, 3 and 6 mg kg -1 were administered in beagle dogs. Moreover, the steady state pharmacokinetics of 1, 3 and 6 mg kg -1 doses were studied. Der