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Pharmacokinetics of Heterologous and Homologous Immunoglobulin G, F(ab‘)2 and Fab after Intravenous Administration in the Rat

✍ Scribed by MARTINE I. BAZIN-REDUREAU; CATHERINE B. RENARD; JEAN-MICHEL G. SCHERRMANN


Book ID
118110656
Publisher
Pharmaceutical Press
Year
1997
Tongue
English
Weight
489 KB
Volume
49
Category
Article
ISSN
2042-7158

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✍ Mojdeh Maboudian-Esfahani; Dion R. Brocks 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 115 KB 👁 2 views

The pharmacokinetics of the anticholinergic drug ethopropazine (ET) have been studied in the rat after intravenous (i.v.) and oral administration. After i.v. doses of 5 and 10 mg/kg ET HCl, mean +/- S.D. plasma AUC were 9836 +/- 2129 (n = 4 rats) and 13096 +/- 4186 ng h/mL (n = 5 rats), respectively