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Pharmacokinetics of gamithromycin in cattle with comparison of plasma and lung tissue concentrations and plasma antibacterial activity

✍ Scribed by R. A. HUANG; L. T. LETENDRE; N. BANAV; J. FISCHER; B. SOMERVILLE


Book ID
108885452
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
324 KB
Volume
33
Category
Article
ISSN
0140-7783

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✍ Suman Penugonda; Hitesh K. Agarwal; Keykavous Parang; Reza Mehvar πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 165 KB

The plasma and tissue disposition of two novel dextran prodrugs of methylprednisolone (MP) containing one (DMP-1) or five (DMP-5) amino acids as linkers were studied in rats. Single 5-mg/kg doses (MP equivalent) of each prodrug or MP were administered intravenously, and blood and tissue samples were