Pharmacokinetics of fusidic acid after a single dose of a new paediatric suspension
✍ Scribed by P. Bourget; J.–F. Duhamel; H. Sørensen; R. Roiron
- Book ID
- 114738414
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 525 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0269-4727
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Twelve healthy children in three age groups anaesthetized for minor surgery were given a single oral dose of tiaprofenic acid (3 mg.kg-1) (TA). Seven blood samples and zero to 8 and 8 to 24 h urines were collected. TA concentrations in plasma and urine were measured by HPLC. No significant differenc
The pharmacokinetics of valproic acid (VPA) was investigated in six healthy volunteers. This was done by monitoring total and free (unbound) valproic acid levels in the serum, and the amount of one of its metabolites, VPA glucuronide, in the urine as a function of time, after a single dose administr