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Pharmacokinetics of fluorouracil by intravenous or intraarterial injection

✍ Scribed by Geng Baoqin; Zhu Yonglian

Book ID
112824194
Publisher
Chinese Anti-Cancer Association
Year
1989
Tongue
English
Weight
184 KB
Volume
1
Category
Article
ISSN
1000-9604

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✍ Magnus Andersson; Lennart DomellΓΆf; SΓΆren HΓ€ggmark; GΓΆran Johansson; Sebastian R πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 454 KB

Reported 5-FU-induced cardiac side effects may be explained by drug-induced hemodynamic changes and/or by direct myocardial toxicity due to regional drug uptake. This question was studied in 11 animals given constant infusions and 6 animals given bolus 5-FU infusions into the hepatic artery. Six ani