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Pharmacokinetics of flunitrazepam following single- and multiple-dose oral administration to healthy human subjects

✍ Scribed by H. G. Boxenbaum; H. N. Posmanter; T. Macasieb; K. A. Geitner; R. E. Weinfeld; J. D. Moore; A. Darragh; D. A. O'Kelly; L. Weissman; S. A. Kaplan

Book ID: 112472607
Publisher: Springer
Year: 1978
Tongue: English
Weight: 469 KB
Volume: 6
Category: Article
ISSN: 1573-8744
DOI: 10.1007/bf01060092

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## Abstract Dolasetron is a 5‐hydroxytryptamine antagonist active at type III receptors; it is presently undergoing clinical evaluation for the reduction/prevention of cancer chemotherapyinduced nausea and vomiting. A previous study demonstrated that following intravenous administration to healthy