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Pharmacokinetics of flosequinan in patients with heart failure

โœ Scribed by D. P. Nicholls; A. Droogan; C. A. Carson; I. C. Taylor; A. P. Passmore; G. D. Johnston; M. Kendall; D. Dutka; G. K. Morris; L. M. Underwood; I. D. Hind


Publisher
Springer
Year
1996
Tongue
English
Weight
225 KB
Volume
50
Category
Article
ISSN
0031-6970

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The acute central haemodynamic and neuroendocrine effects of intravenous flosequinan were studied in a group of 10 patients with severe heart failure. Flosequinan improved cardiac output by a maximum of 1.59 l.min-1, it reduced pulmonary capillary wedge pressure by 11.9 mm Hg and it also caused a re