Pharmacokinetics of fenfluramine enantiomers in man
β Scribed by S. Caccia; M. Ballabio; P. De Ponte
- Book ID
- 113006259
- Publisher
- Springer-Verlag
- Year
- 1979
- Tongue
- English
- Weight
- 420 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0378-7966
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The chiral beta-blocker acebutolol (AC) is marketed as a racemic mixture. Both AC and its major metabolite, diacetotol (DC), are chiral, the S-enantiomer possessing beta-blocking activity. The pharmacokinetics of AC and DC enantiomers was determined in 12 healthy subjects following oral administrati