## Abstract In rats pretreated with dexamethasone (an inducer of CYP3A1/2 in rats) and troleandomycin (an inhibitor of CYP3A1/2 in rats), the area under the plasma concentrationβtime curve from time zero to time infinity (__AUC__) values of clarithromycin were significantly smaller (365 compared wi
Pharmacokinetics of etoposide in rats with uranyl nitrate (UN)-induced acute renal failure (ARF): Optimization of the duration of UN dosing
β Scribed by P. Venkatesh; T. Harisudhan; Hira Choudhury; Ramesh Mullangi; Nuggehally R. Srinivas
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 762 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0378-7966
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π SIMILAR VOLUMES
The effects of glucose on CYP2E1 expression in rats with acute renal failure induced by uranyl nitrate (U-ARF) have been reported. CYP2E1 was significantly induced (2.3-fold) in rats with U-ARF compared with that in control rats. In contrast, CYP2E1 expression was significantly decreased in rats wit
Although acute renal failure (ARF) has been an area of extensive research in recent decades, our understanding of ARF is far from complete. Organic cations (OCs) are primarily excreted via vectorial transport by various renal organic cation transporters (OCTs). It is reasonable to assume that ARF ma