Pharmacokinetics of diclofenac sodium after intramuscular administration in combination with triamcinolone acetate

The pharmacokinetics and pharmacodynamic

The pharmacokinetics and pharmacodynamics of metoprolol after conventional and controlled-release administration in combination with hydrochlorothiazide in healthy volunteers

✍ P. Lundborg; B. Abrahamsson; I. Wieselgren; M. Walter 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 302 KB

We have studied a controlled-release formulation containing metoprolol 100 mg and hydrochlorothiazide 12.5 mg. We compared the pharmacokinetics of both substances and the pharmacodynamics of metoprolol with those of a conventional combination tablet. The controlled-release formulation gave less vari