Pharmacokinetics of dexamethasone in a rat model of rheumatoid arthritis
β Scribed by Justin C. Earp; Nancy A. Pyszczynski; Diana S. Molano; William J. Jusko
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 105 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0142-2782
- DOI
- 10.1002/bdd.626
No coin nor oath required. For personal study only.
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## Abstract ## Objective There is evidence supporting a therapeutic range for methotrexate polyglutamate (MTXGlu) concentrations in the treatment of rheumatoid arthritis (RA). Knowledge of the pharmacokinetics of MTXGlu~1β5~ is required for optimal timing of blood sampling. The aim of this study w
## Abstract ## Objective Antibodies directed to citrullineβcontaining proteins are highly specific for rheumatoid arthritis (RA) and can be detected in up to 80% of patients with RA. Citrulline is a nonstandard amino acid that can be incorporated into proteins only by posttranslational modificatio