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Pharmacokinetics of daunorubicin as a determinant of response in acute myeloid leukemia

✍ Scribed by E. Kokenberg; J. van der Steuijt; B. Löwenberg; K. Nooter; P. Sonneveld


Book ID
113238651
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
99 KB
Volume
10
Category
Article
ISSN
0145-2126

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We have used laser-assisted confocal microscopy to evaluate the intracellular distribution of daunorubicin (DNR) in acute myeloid leukemia (AML) cell lines and fresh AML cells according to their differentiation phenotype. In KG1a, KG1, TF-1 and HEL cells, which express the early differentiation mark