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Pharmacokinetics of buccal and intranasal lorazepam in healthy adult volunteers

✍ Scribed by Mark Anderson; Parag Tambe; Helen Sammons; Hussain Mulla; Richard Cole; Imti Choonara


Publisher
Springer
Year
2011
Tongue
English
Weight
152 KB
Volume
68
Category
Article
ISSN
0031-6970

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## Abstract Selegiline is beneficial to Parkinsonian patients as an adjunct to levodopa therapy. A sensitive fluorimetric assay based on ibhibition of rat brain monoamine oxidase‐B (MAO‐B) __in vitro__ has been developed to study the pharmacokinetics of selegiline. This method quantitates selegilin