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Pharmacokinetics of brequinar sodium (NSC 368390; DUP 785) in cerebrospinal fluid

โœ Scribed by Schwartsmann, G.; van der Vijgh, W.J.F.; Klein, I.; van Groeningen, C.J.; Vermorken, J.B.; Pinedo, H.M.


Book ID
123114439
Publisher
Elsevier Science
Year
1988
Weight
164 KB
Volume
24
Category
Article
ISSN
0277-5379

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Distribution of the novel anticancer dru
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The distribution of the novel anticancer drug candidate Brequinar Sodium (DuP 785, NSC 368390) was studied in control mice and mice implanted subcutaneously with human colon carcinoma xenografts. Mice were given radiolabeled 14C-Brequinar Sodium intravenously. Brequinar concentrations in blood and v