Pharmacokinetics of ketoprofen enantiome
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R. T. Foster; F. Jamali; A. S. Russell; S. R. Alballa
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Article
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1988
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John Wiley and Sons
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English
โ 516 KB
Ketoprofen (KT), a chiral nonsteroidal anti-inflammatory drug (NSAID), is marketed and used as a racemic mixture. In healthy volunteers, negligible differences have been reported between the plasma time courses of KT enantiomers. Using a stereospecific high-performance liquid chromatographic (HPLC)