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Pharmacokinetics of 5-fluorouracil and its catabolites determined by 19F nuclear magnetic resonance spectroscopy for a patient on chronic hemodialysis

✍ Scribed by Jens Rengelshausen; William E. Hull; Vedat Schwenger; Christoph Göggelmann; Ingeborg Walter-Sack; Jürgen Bommer


Book ID
114463526
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
63 KB
Volume
39
Category
Article
ISSN
0272-6386

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In vivo 19F nuclear magnetic resonance (NMR) spectroscopy has the potential to non-invasively measure the concentration of 5-fluorouracil (FUra) and some of its metabolites in humans. Such a measure could be useful in predicting and optimizing the response of individual patients treated with FUra. T