𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans

✍ Scribed by M. Depré; E. Ehrich; A. Van Hecken; I. De Lepeleire; A. Dallob; P. Wong; A. Porras; B. J. Gertz; P. J. De Schepper


Publisher
Springer
Year
2000
Tongue
English
Weight
155 KB
Volume
56
Category
Article
ISSN
0031-6970

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Clinical pharmacokinetics and tolerabili
✍ J. H. G. Jonkman; G. Bianchetti; G. Grasmeijer; B. Oosterhuis; J. F. Thiercelin; 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 515 KB

In a double-blind, placebo-controlled, cross-over experiment in 21 healthy male volunteers, aged 19 to 27 y, the pharmacokinetics and tolerance of the new anxiolytic drug alpidem (SL80.0342) and its three major metabolites were studied after single doses of 25, 50, 100 and 200 mg. Plasma concentrati

Effect of inflammation on kidney functio
✍ Sam Harirforoosh; Fakhreddin Jamali 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB 👁 1 views

## Abstract Chronic arthritis adversely affects glomerular function and nonsteroidal anti‐inflammatory drugs (NSAIDs) reduce electrolyte urinary excretion. In addition, both acute and chronic inflammations may alter clearance of drugs. We studied (a) the effects of inflammation on the renal functio

Enantioselective pharmacokinetics of eth
✍ Dr. Wayne D. Hooper; Nerida J. O'shea; Mi Sui Qing 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 655 KB

Racemic ethotoin (lo00 mg) was administered orally as a single dose to six healthy adult volunteers. Blood samples were collected at appropriate times for 120 h following the dose. Ethotoin was quantified enantioselectively in plasma using a novel chiral column HPLC procedure. One of the enantiomers