Pharmacokinetics and toxicity of idarubicin in the rat
β Scribed by Olaf Kuhlmann; Stefan Hofmann; Michael Weiss
- Book ID
- 105737288
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 672 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0378-7966
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We have studied the pharmacokinetics of idarubicin and daunorubicin in a total of 16 leukemic patients treated with one of these drugs associated with aracytine. The AUCs obtained for unchanged drugs were proportional to the dose, and the doseβindependent pharmacokinetic parameters were
Idarubicin-loaded solid lipid nanoparticles (IDA-SLN) and idarubicin in solution were prepared and the two formulations were administered to rats, either by the duodenal route or intravenously (iv). The aim of this research was to study whether the bioavailability of idarubicin can be improved by ad