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Pharmacokinetics and tissue distribution of intraperitoneal paclitaxel with different carrier solutions

โœ Scribed by Faheez Mohamed; Pierre Marchettini; O.Anthony Stuart; PaulH. Sugarbaker

Book ID
105991847
Publisher
Springer
Year
2003
Tongue
English
Weight
243 KB
Volume
52
Category
Article
ISSN
0344-5704

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Carrier proteins determine local pharmac
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โœ Mark A. Lovich; Chris Creel; Kristy Hong; Chao-Wei Hwang; Elazer R. Edelman ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 186 KB

The growing use of local drug delivery to vascular tissues has increased interest in hydrophobic compounds. The binding of these drugs to serum proteins raises their levels in solution, but hinders their distribution through tissues. Inside the arterial interstitium, viscous and steric forces and bi