Pharmacokinetics and tissue distribution of amphotericin B following oral administration of three lipid-based formulations to rats
โ Scribed by Ibrahim, Fady; Gershkovich, Pavel; Sivak, Olena; Wasan, Ellen K.; Wasan, Kishor M.
- Book ID
- 115521653
- Publisher
- Informa plc
- Year
- 2012
- Tongue
- English
- Weight
- 692 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0363-9045
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Model independent pharmacokinetic analysis of intravenous (iv) amphotericin B cochleates (CAMB), a new lipid-based drug delivery system, in mice (0.625 mg/kg) shows a two-phase disposition profile in blood [area under the curve of concentration versus time from time zero to infinity (AUC(0-infinity)
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