Photodynamic therapy (PDT), due to its tumor selectivity, represents an alternative approach to diagnose and treat cervical intra-epithelial neoplasia (CIN) without altering normal surrounding tissue. Our aim was to investigate the pharmacokinetics and the selectivity of 5-aminolevulinic acid (5-ALA
Pharmacokinetics and selectivity of porphyrin synthesis after topical application of hexaminolevulinate in patients with cervical intraepithelial neoplasia
β Scribed by Peter Hillemanns; Xiuli Wang; Hermann Hertel; Vaagn Andikyan; Marija Hillemanns; Herbert Stepp; Philipp Soergel
- Book ID
- 113432515
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 460 KB
- Volume
- 198
- Category
- Article
- ISSN
- 1097-6868
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## Abstract ## Background and Objectives Compared to the conventional management of cervical intraepithelial neoplasia (CIN) the potential advantage of photodynamic therapy (PDT) for the treatment of cervical human papilloma virus (HPV)βrelated disease encompasses a minimal invasive procedure with
## Abstract The natural history of highβrisk human papillomavirus (HRHPV) infection after successful treatment of cervical intraepithelial neoplasia (CIN) is not well known. This study was performed to evaluate the rate and pattern of HRHPV infection clearance after successful conization for CIN an