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Pharmacokinetics and protein binding of cefazolin in morbidly obese patients

โœ Scribed by Simone van Kralingen; Margot Taks; Jeroen Diepstraten; Ewoudt M. van de Garde; Eric P. van Dongen; Marinus J. Wiezer; Bert van Ramshorst; Bart Vlaminckx; Vera H. Deneer; Catherijne A. Knibbe


Publisher
Springer
Year
2011
Tongue
English
Weight
197 KB
Volume
67
Category
Article
ISSN
0031-6970

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Significance of protein binding in pharm
โœ Stephan Schmidt; Daniel Gonzalez; Hartmut Derendorf ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 243 KB

The significance of plasma protein binding on drug efficacy and, subsequently, the clinical relevance of changes in protein binding has been controversially discussed for decades. The uncertainty concerning the impact of plasma protein binding on a drug's pharmacological activity is, in part, relate