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Pharmacokinetics and pharmacodynamics of prenicarbanate in human skin fibroblast and keratinocytes


Book ID
117628698
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
134 KB
Volume
4
Category
Article
ISSN
0928-0987

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The uptake of glucocorticoids by cultured human skin keratinocytes and fibroblasts was found to be a rapid, temperature-sensitive process. All glucocorticoids tested accumulated in the cells, and the ratio between the intracellular and extracellular concentrations (q/Co ratio) was higher than 1. For