Pharmacokinetics and pharmacodynamics of
✍
Jack A. Cook; Paula J. Burger; Barbara M. Michniewicz; Gerald D. Nordblom; Gary
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 163 KB
👁 1 views
The purpose of this study was to characterize CI-992 pharmacokinetics and pharmacokinetics/pharmacodynamics (PK/PD) in sodium deplete monkeys. Panels of monkeys were administered CI-992 as a 1 h intravenous infusions (0.1 and 1 mg kg -1 ) or as single oral doses (0, 10, 50, and 100 mg kg -1 ). Mean