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Pharmacokinetics and pharmacodynamics of obidoxime in sarin-poisoned rats

✍ Scribed by C.M. Alioth-Streichenberg; D.M. Bodmer; P.G. Waser


Book ID
113207595
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
842 KB
Volume
108
Category
Article
ISSN
0041-008X

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Pharmacokinetics and efficacies of obido
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The efficacies (ED50) of obidoxime and atropine against paraoxon poisoning in mice were determined by administering the antidotes 5, 20, 40 and 60 min before administration of the organophosphate. With increasing time intervals t between the administration of the antidote and paraoxon, the dose of a