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Pharmacokinetics and Pharmacodynamics of Febuxostat (TMX-67), a Non-Purine Selective Inhibitor of Xanthine Oxidase/Xanthine Dehydrogenase (NPSIXO) in Patients with Gout and/or Hyperuricemia

โœ Scribed by K. Komoriya; S. Hoshide; K. Takeda; H. Kobayashi; J. Kubo; M. Tsuchimoto; T. Nakachi; H. Yamanaka; N. Kamatani


Publisher
John Wiley and Sons
Year
2005
Weight
9 KB
Volume
36
Category
Article
ISSN
0931-7597

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Febuxostat, a novel nonpurine selective
โœ Michael A. Becker; H. Ralph Schumacher Jr.; Robert L. Wortmann; Patricia A. MacD ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 168 KB ๐Ÿ‘ 2 views

## Abstract ## Objective Gout affects โˆผ1โ€“2% of the American population. Current options for treating hyperuricemia in chronic gout are limited. The purpose of this study was to assess the safety and efficacy of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in establishing normal