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Pharmacokinetics and Pharmacodynamics of Entacapone and Tolcapone after Acute and Repeated Administration: A Comparative Study in the Rat

✍ Scribed by Forsberg, M.


Book ID
118006122
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2003
Tongue
English
Weight
375 KB
Volume
304
Category
Article
ISSN
0022-3565

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The distribution, metabolism, and pharmacokinetics of physostigmine (Phy) and the time course of butyrylcholinesterase (BuChE) in plasma and cholinesterase (ChE) activity in brain and muscle and their relationship to Phy concentration were described after oral administration of 3H-Phy (650pg kg-') t