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Pharmacokinetics and Pharmacodynamic Effects of Oral GLP-1 and PYY3-36: A Proof-of-concept Study in Healthy Subjects

✍ Scribed by Beglinger, C; Poller, B; Arbit, E; Ganzoni, C; Gass, S; Gomez-Orellana, I; Drewe, J


Book ID
109845626
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
230 KB
Volume
84
Category
Article
ISSN
0009-9236

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## Abstract ## Objective To assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of the CC chemokine receptor CCR1 antagonist MLN3897 in patients with rheumatoid arthritis (RA) receiving methotrexate (MTX). ## Methods In this phase IIa, proof‐of‐concept study, patients meeting the