Pharmacokinetics and erythropoietic response to human recombinant erythropoietin in healthy men
β Scribed by Vlasses, Peter H; Flaharty, Kristen K; Caro, Jaime; Erslev, Allan; Whalen, John J; Morris, Edward M; Bjornsson, Thorir D
- Book ID
- 109844885
- Publisher
- Nature Publishing Group
- Year
- 1990
- Tongue
- English
- Weight
- 532 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0009-9236
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The pharmacokinetics of recombinant human Epo (rHuEpo) were investigated after subcutaneous administration to horses. Four horses received a single 30 IU kg-' dose of rHuEpo. One horse received three repeated doses of 120 IU kg-' at 48 h intervals. Plasma erythropoietin (Epo) was measured by radioim
## Background: The response to epoetin-alpha treatment is hard to predict in cancer patients receiving chemotherapy. ## Methods: One hundred and seventeen patients were enrolled in this observational study. they had a hemoglobin (hb) level less than or equal to 10.5 g/dl, were receiving platinum