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Pharmacokinetics and Distribution of Ribonuclease and its Monomethoxypoly(Ethylene Glycol) Derivatives in Rats

✍ Scribed by M. Láznı́ček; O. Schiavon; P. Caliceti; F.M. Veronese

Book ID
118770198
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
265 KB
Volume
28
Category
Article
ISSN
1043-6618

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✍ P. Caliceti; O. Schiavon; F. M. Veronese; I. M. Chaiken 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 582 KB

## Abstract The effects of modification of bovine pancreatic ribonuclease A by monomethoxypoly(ethylene glycol) (MPEG) were examined for changes in recognition by antiRNase antibodies, enzymatic activity against low and high molecular weight substrates and conformational stability to temperature el