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Pharmacokinetics and clinical predictors of surfactant redosing in respiratory distress syndrome

✍ Scribed by Paola E. Cogo; Maddalena Facco; Manuela Simonato; Daniele De Luca; Francesca De Terlizi; Umberto Rizzotti; Giovanna Verlato; Maria Paola Bellagamba; Virgilio P. Carnielli


Publisher
Springer
Year
2010
Tongue
English
Weight
200 KB
Volume
37
Category
Article
ISSN
1432-1238

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Surfactant deficiency in newborn infants with hyaline membrane disease (HMD) reduces peripheral airway stability, leading to lung atelectasis, inhomogeneity of distribution of ventilation, ventilation/perfusion mismatch, and hypoxemia. The aim of this study was to evaluate the immediate effect of ex