Pharmacokinetics and biodistribution of a light-chain-shuffled CC49 single-chain Fv antibody construct
โ Scribed by Gabriela Pavlinkova; David Colcher; Barbara J. M. Booth; Apollina Goel; Surinder K. Batra
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 214 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Multivalency is a recognized means of increasing the functional affinity of single-chain Fvs (scFvs) for optimizing tumor uptake. A unique divalent single-chain Fv protein [sc(Fv)2], based on the variable regions of the monoclonal antibody (MAb) CC49, has been generated that differs from other dimer
The plant hormone abscisic acid (ABA) participates in the control of several important physiological processes in plants such as stomata regulation, seed dormancy and stress tolerance. A new strategy was developed to study these phenomena by blocking abscisic acid with intracellularly expressed spec