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Pharmacokinetics and biodistribution of [111In]-avidin and [99mTc]-biotin-liposomes injected in the pleural space for the targeting of mediastinal nodes

โœ Scribed by Luis A Medina; Robert Klipper; William T Phillips; Beth Goins


Book ID
117688002
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
290 KB
Volume
31
Category
Article
ISSN
0969-8051

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Mediastinal node and diaphragmatic targe
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A method for delivering drugs to sites of disease extension in mediastinal nodes is described. Mediastinal node and lymphatic distributions were determined after intracavitary injection of the avidin/biotin-liposome system in normal rats. The effect of the injected dose on lymphatic targeting of lip

Avidin/biotin-liposome system injected i
โœ Luis A. Medina; Sergio M. Calixto; Robert Klipper; William T. Phillips; Beth Goi ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 195 KB

The objective of this study was to develop a more effective liposome-based method for delivering drugs to mediastinal nodes. Nodal uptake was determined after intrapleural injection of the avidin/biotin-liposome system in normal rats. The effect of injection sequence (avidin injected 2 h before biot