A method for delivering drugs to sites of disease extension in mediastinal nodes is described. Mediastinal node and lymphatic distributions were determined after intracavitary injection of the avidin/biotin-liposome system in normal rats. The effect of the injected dose on lymphatic targeting of lip
โฆ LIBER โฆ
Pharmacokinetics and biodistribution of [111In]-avidin and [99mTc]-biotin-liposomes injected in the pleural space for the targeting of mediastinal nodes
โ Scribed by Luis A Medina; Robert Klipper; William T Phillips; Beth Goins
- Book ID
- 117688002
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 290 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0969-8051
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The objective of this study was to develop a more effective liposome-based method for delivering drugs to mediastinal nodes. Nodal uptake was determined after intrapleural injection of the avidin/biotin-liposome system in normal rats. The effect of injection sequence (avidin injected 2 h before biot