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Pharmacokinetics and bioavailability of a sustained-release diltiazem formulation (Mono-Tildiem LP 300 mg) after repeated administration in healthy volunteers

✍ Scribed by G. Bianchetti; C. Dubruc; P. Rosenzweig; V. Sultana; G. Houin

Publisher
Springer
Year
1995
Tongue
English
Weight
580 KB
Volume
48-48
Category
Article
ISSN
0031-6970

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Pharmacokinetics and pharmacodynamics of a slow-release formulation of diltiazem after the administration of a single and repeated doses to healthy volunteers
✍ M. Lefebvre; Y. Lacasse; J. SpΓ©nard; D. Geadah; R. Moisan; D. Gossard; H. Landri πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 782 KB

Diltiazem is a calcium antagonist used in angina pectoris and hypertension. There is little information concerning the slow-release (SR) formulation in the literature. The pharmacokinetics of diltiazem SR (120 mg) have been assessed over a 36 h period in healthy volunteers after single-(SD) and mult