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Pharmacokinetic/pharmacodynamic modeling of antitumor agents encapsulated into liposomes

โœ Scribed by H. Harashima; M. Tsuchihashi; S. Iida; H. Doi; H. Kiwada


Book ID
114176669
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
799 KB
Volume
40
Category
Article
ISSN
0169-409X

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The pharmacokinetics of 3H-Triamcinolone Acetonide-21-palmitate entrapped in liposomes with neutral, negative and positive surface charge was investigated in the male New Zealand White rabbit after a single intravenous bolus injection. Drug concentration-time data monitored in whole blood showed bi-