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Pharmacokinetic/pharmacodynamic modeling for the determination of a cimicoxib dosing regimen in the dog

โœ Scribed by Jeunesse, Elisabeth C; Schneider, Marc; Woehrle, Frederique; Faucher, Mathieu; Lefebvre, Herve P; Toutain, Pierre-Louis

Book ID
121572861
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
548 KB
Volume
9
Category
Article
ISSN
1746-6148

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The kinetic behaviour of the aminoglycoside aminosidine, given at 15 mg/kg intravenously, intramuscularly and subcutaneously, was studied in 5 dogs to determine the appropriate dosage schedule. The pharmacokinetic behaviour of aminosidine in dogs was similar to that in other species, except that it