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Pharmacokinetic study of carbamazepine and its carbamazepine 10,11-epoxide metabolite in a group of female epileptic patients under chronic treatment

✍ Scribed by Julia Moreno; Aurora Belmont; Orlando Jaimes; José A Santos; Guadalupe López; Marı́a G Campos; Octavio Amancio; Patricia Pérez; Gerardo Heinze

Book ID
113466640
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
103 KB
Volume
35
Category
Article
ISSN
0188-4409

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Simultaneous Determination of Carbamazep
Simultaneous Determination of Carbamazepine and Carbamazepine 10,11-Epoxide by Using Microcolumn HPLC: Study of Pharmacokinetics of Carbamazepine in a Volunteer
✍ Maka M. Alexishvili; Marina D. Rukhadze; Vazha M. Okujava 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB 👁 1 views

A highly-sensitive microcolumn HPLC method for the simultaneous determination of carbamazepine and carbamazepine-l0,ll-epoxide in human serum and saliva is described. The method was successfully employed for the study of pharmacokinetics of carbamazepine in humans. After oral administration of 100 a