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Pharmacokinetic Studies of Methotrexate in Plasma and Synovial Fluid Following IV Bolus and Topical Routes of Administration in Dogs

โœ Scribed by G. W. Lu; H. W. Jun; M. T. Dzimianski; H. C. Qiu; J. W. McCall


Book ID
110346497
Publisher
Springer US
Year
1995
Tongue
English
Weight
798 KB
Volume
12
Category
Article
ISSN
0724-8741

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The pharmacokinetic profiles of naproxen in blood and synovial fluid (SF) following topical and i.v. bolus administration in dogs, and the local tissue disposition of the drug following topical and oral administration in rats, were investigated to assess the feasibility of topical delivery of naprox