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Pharmacokinetic Properties of a Novel Tissue-Type Plasminogen Activator Pamiteplase After Single Intravenous Administration to Rats, Dogs, and Monkeys

โœ Scribed by Keishi Oikawa; Hidetaka Kamimura; Takashi Watanabe; Ikuo Miyamoto; Saburo Higuchi


Book ID
117256956
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
139 KB
Volume
101
Category
Article
ISSN
0049-3848

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โœ So H. Kim; Jong W. Kwon; Myung G. Lee ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 224 KB ๐Ÿ‘ 2 views

The pharmacokinetic parameters including tissue distribution and/or biliary excretion of DA-1131, a new carbapenem, were evaluated after intravenous (iv) administration to mice, rats, rabbits, and dogs. After i.v. administration to mice (20, 50, 100, and 200 mg kg-1), rats (50, 100, 200, and 500 mg