Pharmacokinetic profile of two aromatic retinoids (etretinate and acitretin) in the obese zucker rat

Influence of lovastatin on the pharmacok

Influence of lovastatin on the pharmacokinetics, toxicity and immunologic response of cyclosporine in the obese zucker rat

✍ Kurt L. Berens; Kiumars Vadiei; Lane J. Brunner; Kishor M. Wasan; Dr. David R. L 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 591 KB

## Abstract The combined use of lovastatin, a hypolipidemic agent effective in the reduction of cholesterol levels, and the lipophilic immunosuppressant, cyclosporine, was studied in the obese rat model. Pharmacokinetics, immunosuppressive activity, lipid levels, and creatinine clearances were comp