𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pharmacokinetic-pharmacodynamic modelling of the convulsant interaction between norfloxacin and biphenyl acetic acid in rats

✍ Scribed by Sandrine Marchand; Claudine Pariat; Serge Bouquet; Philippe Courtois; William Couet


Book ID
110004939
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
186 KB
Volume
129
Category
Article
ISSN
0007-1188

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Retracted: Convulsant activity and pharm
✍ Bikash Roy; Anirbandeep Bose; Uttam Bhaumik; Ayan Das; Nilendra Chatterjee; Anim 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

A pharmacokinetic-pharmacodynamic (PK-PD) modeling approach was used to investigate the epileptogenic activity of gemifloxacin as a representative antibiotic with concentration-dependent antimicrobial activity. Rats received an intravenous infusion of gemifloxacin at a rate of 4 mg kg of body weight

Extension of the isobolographic approach
✍ Céline Brochot; Sandrine Marchand; William Couet; Andrew Gelman; Frédéric Y. Boi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB 👁 1 views

This work proposes a model to characterize the additivity or the nonadditivity of combinations of more than two agents. Using a Bayesian framework, we modeled the variability between experimental subjects, the errors that occurred during data collection, and the relationship between effects and conc