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Pharmacokinetic-Pharmacodynamic Modeling of the Antibiotic Effect of Piperacillin in Vitro

✍ Scribed by Arno Nolting; Teresa Dalla Costa; Kenneth H. Rand; Hartmut Derendorf

Book ID
110345351
Publisher
Springer US
Year
1996
Tongue
English
Weight
835 KB
Volume
13
Category
Article
ISSN
0724-8741

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A pharmacokinetic (PK)/pharmacodynamic (PD) modeling strategy to explain the data from an in vitro dynamic model is proposed. Two carbapenem antibiotics, doripenem and meropenem, and three Pseudomonas aeruginosa strains were used as example drugs and strains. The PD model we originally developed to