EFFECTS OF DESETHYLAMIODARONE ON THE ELE
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Jahanavi Kharidia; Natalie D. Eddington
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Article
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1996
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John Wiley and Sons
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English
⚖ 666 KB
Desethylamiodarone (DEA), the mjor active metabolite of amiodarone (AMD), plays a significant role in the electrophysiological effects observed during AMD thexapy. The pharmacokinetics and pharmacodynamics of DEA wcre studied in rats. Animals were administered DEA (20 or 40 mg kg-I) and blood sample