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Pharmacokinetic Optimisation of the Treatment of Cancer with High Dose Zidovudine

✍ Scribed by Dr Romano Danesi, Alfredo Falcone, Pier Franco Conte, Mario Del Tacca

Book ID
119926160
Publisher
Springer International Publishing AG
Year
1998
Tongue
English
Weight
114 KB
Volume
34
Category
Article
ISSN
0312-5963

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Postmenopausal patients with metastatic breast cancer were treated with medroxyprogesterone acetate (MPA) (Clinovir) in dosages between 500 and 1500 mg orally per day. The relation of MPA plasma concentrations and endocrine effects were studied in a longitudinal fashion. MPA exerted suppressive effe