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Pharmacokinetic modelling of solute disposition in multiple indicator dilution studies of the perfused placental lobule

โœ Scribed by R.L. Rasiah; R.S. Addison; R.D. Purves; R.H. Mortimer; G.R. Cannell; M.S. Roberts


Book ID
116092201
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
87 KB
Volume
15
Category
Article
ISSN
0143-4004

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The objectives of this study were to evaluate the transplacental kinetics and effects on placental function of the angiotensin converting enzyme (ACE) inhibitor, enalaprilat, in the dually perfused human placental lobule system. When placed in the maternal perfusate at a high therapeutic serum conce