Physiologically based pharmacokinetic mo
β
Shweta R. Urva; Victor C. Yang; Joseph P. Balthasar
π
Article
π
2010
π
John Wiley and Sons
π
English
β 322 KB
Antibodies directed against tumor associated antigens are being increasingly used for detection and treatment of cancers; however, there is an incomplete understanding of the physiological determinants of antibody pharmacokinetics and tumor distribution. The purpose of this study is to (a) compare t