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Pharmacokinetic interations between NSAIDs (indomethacin or sulindac) and H2-receptor antagonists (cimetidine or ranitidine) in human volunteers

✍ Scribed by Vincenenx, Phillipe; Carbon, Claude; Delhotal-Landes, Brigitte; Flouvat, Bernard; Liote, François; Abel, Laurent; Meyer, Philippe


Book ID
109844394
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
789 KB
Volume
44
Category
Article
ISSN
0009-9236

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A possible interaction between the calcium antagonist nimodipine and the H2-receptor antagonists cimetidine and ranitidine has been investigated in two separate studies in healthy subjects. In eight young volunteers the concomitant administration of nimodipine 30 mg t.i.d. and cimetidine 1000 mg/d f